CLINICAL TRIAL SERVICES

The Buffalo Neuroimaging Analysis Center (BNAC) is a dedicated research center that has expertise in traumatic brain injury and concussion clinical trials. Our team uses both qualitative and quantitative analysis of magnetic resonance imaging (MRI), positron emission tomography (PET) and optical coherence tomography (OCT) to better understand the onset, progression, and treatment of these brain injuries. We served as Clinical Core Lab for a number of traumatic brain injury and concussion clinical trials. 

In collaboration with the University at Buffalo Concussion Management Clinic, BNAC has been involved in a number of government and foundation research grants that explored imaging outcomes in order to better understand treatment protocols for sports-related concussion, traumatic brain injuries and various concussion symptoms. In particular, BNAC is engaged in researching pathophysiology of the exercise-based concussion protocols, together with our collaborators, John J. Leddy, MD and Barry S. Willer, PhD, and has used novel methods for understanding the dyregulation of the autonomic system and cerebral blood flow. 

For more information about imaging endpoints, click here.

FEATURED RECENT TRAUMATIC BRAIN INJURY AND CONCUSSION STUDIES

  • Zivadinov R, Polak P, Schweser F, Bergsland N, Hagemeier J, Dwyer MG, Ramasamy DP, Baker JG, Leddy JJ, Willer BS (2018) Multimodal Imaging of Retired Professional Contact Sport Athletes Does Not Provide Evidence of Structural and Functional Brain Damage. J Head Trauma Rehabil 33:E24-E32 [Open article]

  • Polak P, Leddy JJ, Dwyer MG, Willer B, Zivadinov R (2015) Diffusion tensor imaging alterations in patients with postconcussion syndrome undergoing exercise treatment: a pilot longitudinal study. J Head Trauma Rehabil 30:E32-42 [Open article]

  • Leddy JJ, Cox JL, Baker JG, Wack DS, Pendergast DR, Zivadinov R, Willer B (2013) Exercise treatment for postconcussion syndrome: a pilot study of changes in functional magnetic resonance imaging activation, physiology, and symptoms. J Head Trauma Rehabil 28:241-249 [Open article]

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CONTACT OUR TEAM TODAY

Part of BNAC’s mission is to help share our tools and experience with our colleagues and other industry partners. If you need help with managing a medical imaging trial related to traumatic brain injury or concussion, please reach out to discuss how we can assist. Our group brings decades of experience and expertise to every collaborative study and service partnership.  

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