Transcatheter Aortic Valve Replacement

Clinical trial Services

The Buffalo Neuroimaging Analysis Center (BNAC) is a dedicated research center that has expertise covering cerebral protection devices for transcatheter aortic valve replacement (TAVR) procedures. Our researchers utilize both qualitative and quantitative analysis of positron emission tomography (PET), magnetic resonance imaging (MRI), computerized tomography (CT) and magnetic resonance and digital subtraction angiography for clinical research. This includes preclinical and clinical phase I, II, III, and IV trials related to TAVR procedures and cerebral protection devices. 

RECENT Published Research 

  • Lazar RM, Pavol MA, Bormann T, Dwyer MG, Kraemer C, White R, Zivadinov R, Wertheimer JC, Thone-Otto A, Ravdin LD, Naugle R, Mechanic-Hamilton D, Garmoe WS, Stringer AY, Bender HA, Kapadia SR, Kodali S, Ghanem A, Linke A, Mehran R, Virmani R, Nazif T, Parhizgar A and Leon MB (2018). "Neurocognition and Cerebral Lesion Burden in High-Risk Patients Before Undergoing Transcatheter Aortic Valve Replacement: Insights From the SENTINEL Trial." JACC Cardiovasc Interv 11(4): 384-392. [Open Article]
  • Kapadia SR, Kodali S, Makkar R, Mehran R, Lazar RM, Zivadinov R, Dwyer MG, Jilaihawi H, Virmani R, Anwaruddin S, Thourani VH, Nazif T, Mangner N, Woitek F, Krishnaswamy A, Mick S, Chakravarty T, Nakamura M, McCabe JM, Satler L, Zajarias A, Szeto WY, Svensson L, Alu MC, White RM, Kraemer C, Parhizgar A, Leon MB, Linke A and Investigators ST (2017). "Protection Against Cerebral Embolism During Transcatheter Aortic Valve Replacement." J Am Coll Cardiol 69(4): 367-377. [Open Article]
  • Mokin M, Zivadinov R, Dwyer MG, Lazar RM, Hopkins LN and Siddiqui AH (2017). "Transcatheter aortic valve replacement: perioperative stroke and beyond." Expert Rev Neurother 17(4): 327-334. [Open Article]
  • Haussig S, Mangner N, Dwyer MG, Lehmkuhl L, Lucke C, Woitek F, Holzhey DM, Mohr FW, Gutberlet M, Zivadinov R, Schuler G and Linke A (2016). "Effect of a Cerebral Protection Device on Brain Lesions Following Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis: The CLEAN-TAVI Randomized Clinical Trial." JAMA 316(6): 592-601. [Open Article]

Contact Our Center Today

Please contact us to speak about clinical trials or any academic interest to join or collaborate with BNAC related to transcatheter aortic valve replacement. Our team of qualified and board-certified imaging specialists is ready to assist with any medical imaging trial you have in mind.