Dejan Jakimovski, MD, PhD, presents first research to use the sNfL biomarker to affirm the link between brain blood flow and neuronal damage associated with MS
At the American Academy of Neurology Annual Meeting this week, Clinical Research Director Dejan Jakimovski, MD, PhD, presented findings of a recent study, conducted with BNAC colleagues Drs. Niels Bergsland and Michael Dwyer, that explored the correlation between blood flow to the brain and neuronal damage associated with multiple sclerosis. In an interview with the editors of NeurologyLive®, Jakimovski explains how the study builds on BNAC’s earlier research establishing that people with MS who have lower cerebral arterial blood flow, or CABF, have worse cognitive performance. The new study shows, using a measurable biomarker of neuronal damage, that diminished blood flow is contributing to the destruction of more axons in the brain.
The study may be the first to establish the link between cerebral arterial blood flow (CABF) and serum neurofilament light chain (sNfL), a biomarker of neuronal damage.