Selected Research Studies on Brain Atrophy

2023

  • Jakimovski D, Qureshi F, Ramanathan M, Gehman V, Dwyer MG, Bergsland N, Weinstock-Guttman B, Zivadinov R. Multivariate proteomic analysis and the relationship with microstructural axonal pathology in multiple sclerosis: a longitudinal 5-year study. Brain Comm 2023;13;5(3):fcad183. [Open Article]
  • Jakimovski D, Silva D, Bergsland N, Dwyer MG, Weinstock-Guttman D, Benedict RHB, Riolo J, Dwyer MG, Zivadinov R on behalf of the DeepGRAI Registry Study group. Therapy effect on AI-derived thalamic atrophy using clinical routine MRI protocol: A longitudinal, multi-center, propensity-matched multiple sclerosis study. Mult Scler Rel Dis 2023:74:104708. [Open Article]
  • Pennington P, Weinstock-Guttman B, Kolb C, Jakimovski D, Sacca K, Benedict RHB, Eckert S, Stecker M, Lizarraga A, Dwyer MG, Schumacher CB, Bergsland N, Picco P, Bernitsas E, Zabad R, Pardo G, Negroski D, Belkin M, Hojnacki D, Zivadinov R. Communicating the relevance of neurodegeneration and brain atrophy to multiple sclerosis patients: patient, provider and researcher perspectives. J Neurol 2023;270(2):1120-1126. [Open Article]

2022

  • Pennington P, Weinstock-Guttman B, Kolb C, Jakimovski D, P Sacca K, Benedict RHB, Eckert S,
    Stecker M, Lizarraga A, Dwyer MG, Schumacher CB, Bergsland N, Picco P, Bernitsas E, Zabad R,
    Pardo G, Negroski D, Belkin M, Hojnacki D, Zivadinov R. Communicating the relevance of
    neurodegeneration and brain atrophy to multiple sclerosis patients: patient, provider and
    researcher perspectives. J Neurol 2022;doi:10.1007/s00415-022-11405-3. [Open Article]
  • Zivadinov R, Bergsland N, Jakimovski D, Weinstock-Guttman D, Benedict RH, Riolo J, Silva D,
    Dwyer MG, on behalf of the DeepGRAI Registry Study group. Thalamic atrophy measured by
    artificial intelligence in a multi-center clinical routine real-word study is associated with disability
    progression. JNNP 2022;doi:10.1136/jnnp-2022-329333. [Open Article]
  • Sandroff BM, Motl RW, Román CAF, Wylie GR, DeLuca J, Cutter GR, Benedict RHB, Dwyer MG,
    Zivadinov R. Thalamic atrophy moderates associations among aerobic fitness, cognitive
    processing speed, and walking endurance in persons with multiple sclerosis. J Neurol
    2022;269(10):5531-5540. [Open Article]
  • Lyman C, U Lee D, U Ferrari H, U Fuchs TA, P Bergsland N, Jakimovski D, P Weinstock-Guttmann B,
    Zivadinov R, Dwyer MG. MRI-based thalamic volumetry in multiple sclerosis using FSL-FIRST:
    Systematic assessment of common error modes. J Neuroimaging 2022:32(2)245-252. [Open Article]
  • Carolus K, Fuchs TA, Bergsland N, Ramasamy DP, Tran H, Uher T, Horakova D, Vaneckova M, Havrdova E, Benedict RHB, Zivadinov R, Dwyer MG (2022). Time course of lesion-induced atrophy in multiple sclerosis. J Neurol;doi:10.1007/s00415-022-11094-y. [Open article]
  • Jakimovski D, Zivadinov R, Bergsland N, Oh J, Martin M, Shinohara RT, Bakshi R, Calabresi PA, Papinutto N, Pelletier D, Dwyer MG on behalf of North American Imaging in Multiple Sclerosis (NAIMS) (2022). Multi-site reproducibility of lateral ventricular volume using the NAIMS cooperative pilot dataset. J Neuroimaging;doi:10.1111/jon.12998. [Open article]
  • Lyman C,U Lee D,U Ferrari H,U Fuchs TA,P Bergsland N, Jakimovski D,P Weinstock-Guttmann B, Zivadinov R, Dwyer MG (2022). MRI-based thalamic volumetry in multiple sclerosis using FSL-FIRST: Systematic assessment of common error modes. J Neuroimaging:32(2)245-252. [Open article]
  •  

2021

  • Barnett M, Bergsland N, Weinstock-Guttman B, Butzkueven H, Kalincik T, Desmond P, Gaillard F, van Pesch V, Ozakbas S, Rojas JI, Boz C, Altintas A, Wang C, Dwyer MG, Yang S, Jakimovski D, Kyle K, Ramasamy DP, Zivadinov R (2021) Brain atrophy and lesion burden are associated with disability progression in a multiple sclerosis real-world dataset using only T2-FLAIR: The NeuroSTREAM MSBase study. NeuroImage Clinical 32:102802 [Open article]
  • Fuchs TA, Dwyer MG, Jakimovski D, Bergsland N, Ramasamy DP, Weinstock-Guttman B, Hb Benedict R, Zivadinov R (2021) Quantifying disease pathology and predicting disease progression in multiple sclerosis with only clinical routine T2-FLAIR MRI. NeuroImage Clinical 31:102705 [Open article]
  • Hildesheim FE, Benedict RHB, Zivadinov R, Dwyer MG, Fuchs T, Jakimovski D, Weinstock-Guttman B, Bergsland N (2021) Nucleus basalis of Meynert damage and cognition in patients with multiple sclerosis. J Neurol [Open article]
  • Dwyer M, Lyman C, Ferrari H, Bergsland N, Fuchs TA, Jakimovski D, Schweser F, Weinstock-Guttmann B, Benedict RHB, Riolo J, Silva D, Zivadinov R (2021) DeepGRAI (Deep Gray Rating via Artificial Intelligence): Fast, feasible, and clinically relevant thalamic atrophy measurement on clinical quality T2-FLAIR MRI in multiple sclerosis. NeuroImage Clinical 30:102652 [Open article]
  • Ontaneda D, Raza PC, Mahajan KR, Arnold DL, Dwyer MG, Gauthier SA, Greve DN, Harrison DM, Henry RG, Li DKB, Mainero C, Moore W, Narayanan S, Oh J, Patel R, Pelletier D, Rauscher A, Rooney WD, Sicotte NL, Tam R, Reich DS, Azevedo CJ, North American Imaging in Multiple Sclerosis C (2021) Deep grey matter injury in multiple sclerosis: a NAIMS consensus statement. Brain 144:1974-1984 [Open article]
  • Jacobsen C, Zivadinov R, Myhr KM, Dalaker TO, Dalen I, Benedict RH, Bergsland N, Farbu E (2021) Brain atrophy and clinical characteristics predicting SDMT performance in multiple sclerosis: A 10-year follow-up study. Mult Scler J Exp Transl Clin 7:2055217321992394 [Open article]
  • Uher T, Bergsland N, Krasensky J, Dwyer MG, Andelova M, Sobisek L, Havrdova EK, Horakova D, Zivadinov R, Vaneckova M (2021) Interpretation of Brain Volume Increase in Multiple Sclerosis. J Neuroimaging 31:401-407 [Open article]
  • Jakimovski D, Zivadinov R, Bergsland N, Ramasamy DP, Hagemeier J, Genovese AV, Hojnacki D, Weinstock-Guttman B, Dwyer MG (2021) Clinical feasibility of longitudinal lateral ventricular volume measurements on T2-FLAIR across MRI scanner changes. NeuroImage Clinical 29:102554 [Open article]
  • Uher T, Krasenky J, Malpas C, Bergsland N, Dwyer MG, Kubala Havrdova E, Vaneckova M, Horakova D, Zivadinov R, Kalincik T (2021) Evolution of Brain Volume Loss Rates in Early Stages of Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm 8 [Open article]

2020

  • Uher T, Bergsland N, Krasensky J, Dwyer MG, Andelova M, Sobisek L, Havrdova EK, Horakova D, Zivadinov R, Vaneckova M (2020) Interpretation of Brain Volume Increase in Multiple Sclerosis. J Neuroimaging [Open article]
  • Bergsland N, Benedict RHB, Dwyer MG, Fuchs TA, Jakimovski D, Schweser F, Tavazzi E, Weinstock-Guttman B, Zivadinov R (2020) Thalamic Nuclei Volumes and Their Relationships to Neuroperformance in Multiple Sclerosis: A Cross-Sectional Structural MRI Study. J Magn Reson Imaging:e27389 [Open article]
  • Ghione E, Bergsland N, Dwyer MG, Hagemeier J, Jakimovski D, Ramasamy DP, Hojnacki D, Lizarraga AA, Kolb C, Eckert S, Weinstock-Guttman B, Zivadinov R (2020) Disability Improvement Is Associated with Less Brain Atrophy Development in Multiple Sclerosis. AJNR Am J Neuroradiol 41:1577-1583 [Open article]
  • Jakimovski D, Zivadinov R, Bergsland N, Ramasamy DP, Hagemeier J, Weinstock-Guttman B, Kolb C, Hojnacki D, Dwyer MG (2020) Sex-Specific Differences in Life Span Brain Volumes in Multiple Sclerosis. J Neuroimaging 30:342-350 [Open article]
  • Jakimovski D, Bergsland N, Dwyer MG, Hagemeier J, Ramasamy DP, Szigeti K, Guttuso T, Lichter D, Hojnacki D, Weinstock-Guttman B, Benedict RHB, Zivadinov R (2020) Long-standing multiple sclerosis neurodegeneration: volumetric magnetic resonance imaging comparison to Parkinson's disease, mild cognitive impairment, Alzheimer's disease, and elderly healthy controls. Neurobiol Aging 90:84-92 [Open article]
  • Ghione E, Bergsland N, Dwyer MG, et al. Disability Improvement Is Associated with Less Brain Atrophy Development in Multiple Sclerosis. AJNR Am J Neuroradiol 2020;41:1577-1583. [Open article]
  • Jakimovski D, Zivadinov R, Bergsland N, et al. Sex-Specific Differences in Life Span Brain Volumes in Multiple Sclerosis. J Neuroimaging 2020;30:342-350.
  • Jakimovski D, Bergsland N, Dwyer MG, et al. Long-standing multiple sclerosis neurodegeneration: volumetric magnetic resonance imaging comparison to Parkinson's disease, mild cognitive impairment, Alzheimer's disease, and elderly healthy controls. Neurobiol Aging 2020;90:84-92.
  • Jacobsen C, Zivadinov R, Myhr KM, Dalaker TO, Dalen I, Bergsland N and Farbu E (2020). "Brain atrophy and employment in multiple sclerosis patients: a 10-year follow-up study." Mult Scler J Exp Transl Clin 6(1): 2055217320902481. [Open article]
  • Tavazzi E, Bergsland N, Kuhle J, et al. A multimodal approach to assess the validity of atrophied T2-lesion volume as an MRI marker of disease progression in multiple sclerosis. J Neurol 2020;267:802-811. [Open article]
  • Fuchs TA, Benedict RH, Wilding G, et al. Trait Conscientiousness predicts rate of brain atrophy in multiple sclerosis. Mult Scler 2020;26:1433-1436. [Open article]

2019

  • Jakimovski D, Kuhle J, Ramanathan M, Barro C, Tomic D, Hagemeier J, Kropshofer H, Bergsland N, Leppert D, Dwyer MG, Michalak Z, Benedict RHB, Weinstock-Guttman B and Zivadinov R (2019). "Serum neurofilament light chain levels associations with gray matter pathology: a 5-year longitudinal study." Ann Clin Transl Neurol 6(9): 1757-1770. [Open article]
  • Genovese AV, Hagemeier J, Bergsland N, Jakimovski D, Dwyer MG, Ramasamy DP, Lizarraga AA, Hojnacki D, Kolb C, Weinstock-Guttman B and Zivadinov R (2019). "Atrophied Brain T2 Lesion Volume at MRI Is Associated with Disability Progression and Conversion to Secondary Progressive Multiple Sclerosis." Radiology 293(2): 424-433. [Open article]
  • Zivadinov R, Horakova D, Bergsland N, Hagemeier J, Ramasamy DP, Uher T, Vaneckova M, Havrdova E and Dwyer MG (2019). "A Serial 10-Year Follow-Up Study of Atrophied Brain Lesion Volume and Disability Progression in Patients with Relapsing-Remitting MS." AJNR Am J Neuroradiol 40(3): 446-452. [Open article]
  • Ghione E, Bergsland N, Dwyer MG, Hagemeier J, Jakimovski D, Paunkoski I, Ramasamy DP, Carl E, Hojnacki D, Kolb C, Weinstock-Guttman B and Zivadinov R (2019). "Aging and Brain Atrophy in Multiple Sclerosis." J Neuroimaging 29(4): 527-535. [Open article]

2018

  • Dwyer MG, Bergsland N, Ramasamy DP, Jakimovski D, Weinstock-Guttman B and Zivadinov R (2018). "Atrophied Brain Lesion Volume: A New Imaging Biomarker in Multiple Sclerosis." J Neuroimaging 28(5): 490-495. [Open article]
  • Zivadinov R, Bergsland N and Dwyer MG (2018). "Atrophied brain lesion volume, a magnetic resonance imaging biomarker for monitoring neurodegenerative changes in multiple sclerosis." Quant Imaging Med Surg 8(10): 979-983. [Open article]
  • Uher T, Krasensky J, Sobisek L, Seidl Z, Bergsland N, Dwyer MG, Kubala Havrdova E, Zivadinov R, Horakova D and Vaneckova M (2018). "The Role of High-Frequency MRI Monitoring in the Detection of Brain Atrophy in Multiple Sclerosis." J Neuroimaging 28(3): 328-337. [Open article]
  • Ghione E, Bergsland N, Dwyer MG, Hagemeier J, Jakimovski D, Paunkoski I, Ramasamy DP, Silva D, Carl E, Hojnacki D, Kolb C, Weinstock-Guttman B and Zivadinov R (2018). "Brain Atrophy Is Associated with Disability Progression in Patients with MS followed in a Clinical Routine." AJNR Am J Neuroradiol 39(12): 2237-2242. [Open article]

2017

  • Uher T, Krasensky J, Vaneckova M, Sobisek L, Seidl Z, Havrdova E, Bergsland N, Dwyer MG, Horakova D and Zivadinov R (2017). "A Novel Semiautomated Pipeline to Measure Brain Atrophy and Lesion Burden in Multiple Sclerosis: A Long-Term Comparative Study." J Neuroimaging 27(6): 620-629. [Open article]
  • Belov P, Magnano C, Krawiecki J, Hagemeier J, Bergsland N, Beggs C and Zivadinov R (2017). "Age-related brain atrophy may be mitigated by internal jugular vein enlargement in male individuals without neurologic disease." Phlebology 32(2): 125-134. [Open article]
  • Uher T, Vaneckova M, Sobisek L, Tyblova M, Seidl Z, Krasensky J, Ramasamy D, Zivadinov R, Havrdova E, Kalincik T and Horakova D (2017). "Combining clinical and magnetic resonance imaging markers enhances prediction of 12-year disability in multiple sclerosis." Mult Scler 23(1): 51-61. [Open article]

2016

  • Bergsland N, Zivadinov R, Dwyer MG, Weinstock-Guttman B and Benedict RH (2016). "Localized atrophy of the thalamus and slowed cognitive processing speed in MS patients." Mult Scler 22(10): 1327-1336. [Open article]
  • Zivadinov R, Dwyer MG and Bergsland N (2016). "Brain atrophy measurements should be used to guide therapy monitoring in MS - YES." Mult Scler 22(12): 1522-1524. [Open article]
  • Zivadinov R, Uher T, Hagemeier J, Vaneckova M, Ramasamy DP, Tyblova M, Bergsland N, Seidl Z, Dwyer MG, Krasensky J, Havrdova E and Horakova D (2016). "A serial 10-year follow-up study of brain atrophy and disability progression in RRMS patients." Mult Scler 22(13): 1709-1718. [Open article]
  • Zivadinov R, Jakimovski D, Gandhi S, Ahmed R, Dwyer MG, Horakova D, Weinstock-Guttman B, Benedict RR, Vaneckova M, Barnett M and Bergsland N (2016). "Clinical relevance of brain atrophy assessment in multiple sclerosis. Implications for its use in a clinical routine." Expert Rev Neurother: 1-17. [Open article]

2015

  • Uher T, Horakova D, Kalincik T, Bergsland N, Tyblova M, Ramasamy DP, Seidl Z, Vaneckova M, Krasensky J, Havrdova E and Zivadinov R (2015). "Early magnetic resonance imaging predictors of clinical progression after 48 months in clinically isolated syndrome patients treated with intramuscular interferon beta-1a." Eur J Neurol 22(7): 1113-1123. [Open article]
  • Varosanec M, Uher T, Horakova D, Hagemeier J, Bergsland N, Tyblova M, Seidl Z, Vaneckova M, Krasensky J, Dwyer MG, Havrdova E and Zivadinov R (2015). "Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome." AJNR Am J Neuroradiol 36(8): 1457-1464. [Open article]

2014

  • Uher T, Benedict RH, Horakova D, Bergsland N, Dusankova JB, Tyblova M, Ramasamy DP, Seidl Z, Vaneckova M, Krasensky J, Havrdova E and Zivadinov R (2014). "Relationship between gray matter volume and cognitive learning in CIS patients on disease-modifying treatment." J Neurol Sci 347(1-2): 229-234. [Open article]
  • Jacobsen C, Hagemeier J, Myhr KM, Nyland H, Lode K, Bergsland N, Ramasamy DP, Dalaker TO, Larsen JP, Farbu E and Zivadinov R (2014). "Brain atrophy and disability progression in multiple sclerosis patients: a 10-year follow-up study." J Neurol Neurosurg Psychiatry 85(10): 1109-1115. [Open article]
  • Uher T, Horakova D, Bergsland N, Tyblova M, Ramasamy DP, Seidl Z, Vaneckova M, Krasensky J, Havrdova E and Zivadinov R (2014). "MRI correlates of disability progression in patients with CIS over 48 months." Neuroimage Clin 6: 312-319. [Open article]

2013

  • Zivadinov R, Havrdova E, Bergsland N, Tyblova M, Hagemeier J, Seidl Z, Dwyer MG, Vaneckova M, Krasensky J, Carl E, Kalincik T and Horakova D (2013). "Thalamic atrophy is associated with development of clinically definite multiple sclerosis." Radiology 268(3): 831-841. [Open article]
  • Benedict RH, Hulst HE, Bergsland N, Schoonheim MM, Dwyer MG, Weinstock-Guttman B, Geurts JJ and Zivadinov R (2013). "Clinical significance of atrophy and white matter mean diffusivity within the thalamus of multiple sclerosis patients." Mult Scler 19(11): 1478-1484. [Open article]
  • Zivadinov R, Bergsland N, Dolezal O, Hussein S, Seidl Z, Dwyer MG, Vaneckova M, Krasensky J, Potts JA, Kalincik T, Havrdova E and Horakova D (2013). "Evolution of Cortical and Thalamus Atrophy and Disability Progression in Early Relapsing-Remitting MS during 5 Years." AJNR Am J Neuroradiol 34(10): 1931-1939. [Open article]
  • Minagar A, Barnett MH, Benedict RH, Pelletier D, Pirko I, Sahraian MA, Frohman E and Zivadinov R (2013). "The thalamus and multiple sclerosis: modern views on pathologic, imaging, and clinical aspects." Neurology 80(2): 210-219. [Open article]
  • Dolezal O, Gabelic T, Horakova D, Bergsland N, Dwyer MG, Seidl Z, Krasensky J, Ramasamy DP, Vaneckova M, Havrdova E and Zivadinov R (2013). "Development of gray matter atrophy in relapsing-remitting multiple sclerosis is not gender dependent: Results of a 5-year follow-up study." Clin Neurol Neurosurg 115 Suppl 1: S42-48. [Open article]
  • Zivadinov R, Tekwe C, Bergsland N, Dolezal O, Havrdova E, Krasensky J, Dwyer MG, Seidl Z, Ramasamy DP, Vaneckova M and Horakova D (2013). "Bimonthly Evolution of Cortical Atrophy in Early Relapsing-Remitting Multiple Sclerosis over 2 Years: A Longitudinal Study." Mult Scler Int 2013: 231345. [Open article]

2012

  • Bergsland N, Horakova D, Dwyer MG, Dolezal O, Seidl ZK, Vaneckova M, Krasensky J, Havrdova E and Zivadinov R (2012). "Subcortical and cortical gray matter atrophy in a large sample of patients with clinically isolated syndrome and early relapsing-remitting multiple sclerosis." AJNR Am J Neuroradiol 33(8): 1573-1578. [Open article]
  • Batista S, Zivadinov R, Hoogs M, Bergsland N, Heininen-Brown M, Dwyer MG, Weinstock-Guttman B and Benedict RH (2012). "Basal ganglia, thalamus and neocortical atrophy predicting slowed cognitive processing in multiple sclerosis." J Neurol 259(1): 139-146. [Open article]
  • Zivadinov R and Pirko I (2012). "Advances in understanding gray matter pathology in multiple sclerosis: are we ready to redefine disease pathogenesis?" BMC Neurol 12: 9. [Open article]

2011

  • Ramasamy DP, Ramanathan M, Cox JL, Antulov R, Weinstock-Guttman B, Bergsland N, Benedict RH, Dwyer MG, Minagar A and Zivadinov R (2011). "Effect of Met66 allele of the BDNF rs6265 SNP on regional gray matter volumes in patients with multiple sclerosis: A voxel-based morphometry study." Pathophysiology 18(1): 53-60. [Open article]

2010

  • Weinstock-Guttman B, Ramanathan M, Hashmi K, Abdelrahman N, Hojnacki D, Dwyer MG, Hussein S, Bergsland N, Munschauer FE and Zivadinov R (2010). "Increased tissue damage and lesion volumes in African Americans with multiple sclerosis." Neurology 74(7): 538-544. [Open article]

2009

  • Zivadinov R, Weinstock-Guttman B, Hashmi K, Abdelrahman N, Stosic M, Dwyer M, Hussein S, Durfee J and Ramanathan M (2009). "Smoking is associated with increased lesion volumes and brain atrophy in multiple sclerosis." Neurology 73(7): 504-510. [Open article]
  • Zivadinov R and Minagar A (2009). "Evidence for gray matter pathology in multiple sclerosis: a neuroimaging approach." J Neurol Sci 282(1-2): 1-4. [Open article]
  • Ramasamy DP, Benedict RH, Cox JL, Fritz D, Abdelrahman N, Hussein S, Minagar A, Dwyer MG and Zivadinov R (2009). "Extent of cerebellum, subcortical and cortical atrophy in patients with MS: a case-control study." J Neurol Sci 282(1-2): 47-54. [Open article]
  • Horakova D, Dwyer MG, Havrdova E, Cox JL, Dolezal O, Bergsland N, Rimes B, Seidl Z, Vaneckova M and Zivadinov R (2009). "Gray matter atrophy and disability progression in patients with early relapsing-remitting multiple sclerosis: a 5-year longitudinal study." J Neurol Sci 282(1-2): 112-119. [Open article]
  • Antulov R, Weinstock-Guttman B, Cox JL, Hussein S, Durfee J, Caiola C, Dwyer MG, Bergsland N, Abdelrahman N, Stosic M, Hojnacki D, Munschauer FE, Miletic D and Zivadinov R (2009). "Gender-related differences in MS: a study of conventional and nonconventional MRI measures." Mult Scler 15(3): 345-354. [Open article]

2008

  • Horakova D, Cox JL, Havrdova E, Hussein S, Dolezal O, Cookfair D, Dwyer MG, Seidl Z, Bergsland N, Vaneckova M and Zivadinov R (2008). "Evolution of different MRI measures in patients with active relapsing-remitting multiple sclerosis over 2 and 5 years: a case-control study." J Neurol Neurosurg Psychiatry 79(4): 407-414. [Open article]

2007

  • Zivadinov R, Weinstock-Guttman B, Benedict R, Tamano-Blanco M, Hussein S, Abdelrahman N, Durfee J and Ramanathan M (2007). "Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain-derived neurotrophic factor." Hum Mol Genet 16(22): 2659-2668. [Open article]

2005

  • Benedict RH, Zivadinov R, Carone DA, Weinstock-Guttman B, Gaines J, Maggiore C, Sharma J, Tomassi MA and Bakshi R (2005). "Regional lobar atrophy predicts memory impairment in multiple sclerosis." AJNR Am J Neuroradiol 26(7): 1824-1831. [Open article]
  • Zivadinov R (2005). "Steroids and brain atrophy in multiple sclerosis." J Neurol Sci 233(1-2): 73-81. [Open article]
  • Zivadinov R, Grop A, Sharma J, Bratina A, Tjoa CW, Dwyer M and Zorzon M (2005). "Reproducibility and accuracy of quantitative magnetic resonance imaging techniques of whole-brain atrophy measurement in multiple sclerosis." J Neuroimaging 15(1): 27-36. [Open article]

2004

  • Locatelli L, Zivadinov R, Grop A and Zorzon M (2004). "Frontal parenchymal atrophy measures in multiple sclerosis." Mult Scler 10(5): 562-568. [Open article]
  • Zivadinov R, Bagnato F, Nasuelli D, Bastianello S, Bratina A, Locatelli L, Watts K, Finamore L, Grop A, Dwyer M, Catalan M, Clemenzi A, Millefiorini E, Bakshi R and Zorzon M (2004). "Short-term brain atrophy changes in relapsing-remitting multiple sclerosis." J Neurol Sci 223(2): 185-193. [Open article]
  • Sanfilipo MP, Benedict RH, Zivadinov R and Bakshi R (2004). "Correction for intracranial volume in analysis of whole brain atrophy in multiple sclerosis: the proportion vs. residual method." Neuroimage 22(4): 1732-1743. [Open article]
  • Zivadinov R and Bakshi R (2004). "Central nervous system atrophy and clinical status in multiple sclerosis." J Neuroimaging 14(3 Suppl): 27S-35S. [Open article]
  • Zivadinov R and Bakshi R (2004). "Role of MRI in multiple sclerosis I: inflammation and lesions." Front Biosci 9: 665-683. [Open article]
  • Zivadinov R and Bakshi R (2004). "Role of MRI in multiple sclerosis II: brain and spinal cord atrophy." Front Biosci 9: 647-664. [Open article]

2003

  • Fabiano AJ, Sharma J, Weinstock-Guttman B, Munschauer FE, 3rd, Benedict RH, Zivadinov R and Bakshi R (2003). "Thalamic involvement in multiple sclerosis: a diffusion-weighted magnetic resonance imaging study." J Neuroimaging 13(4): 307-314. [Open article]
  • Zivadinov R, Locatelli L, Stival B, Bratina A, Grop A, Nasuelli D, Brnabic-Razmilic O and Zorzon M (2003). "Normalized regional brain atrophy measurements in multiple sclerosis." Neuroradiology 45(11): 793-798. [Open article]

2002

  • Zivadinov R and Zorzon M (2002). "Is gadolinium enhancement predictive of the development of brain atrophy in multiple sclerosis? A review of the literature." J Neuroimaging 12(4): 302-309. [Open article]

2001

  • Zivadinov R, Sepcic J, Nasuelli D, De Masi R, Bragadin LM, Tommasi MA, Zambito-Marsala S, Moretti R, Bratina A, Ukmar M, Pozzi-Mucelli RS, Grop A, Cazzato G and Zorzon M (2001). "A longitudinal study of brain atrophy and cognitive disturbances in the early phase of relapsing-remitting multiple sclerosis." J Neurol Neurosurg Psychiatry 70(6): 773-780. [Open article]