Aging And Dementia Studies


  • Jakimovski D,P Zivadinov R, Weinstock Z,G Fuchs TA, Dwyer MG, Bergsland , Weinstock-Guttman B, Benedict RHB. Cortical thickness and cognitive performance of elderly with multiple sclerosis. J Neurol 2023:doi:10.1007/s00415-023-11945-2. [Open Article]


  • Jakimovski D, Eckert SP, Zivadinov R, Weinstock-Guttman B, Considering patient age when treating multiple sclerosis across the adult lifespan. Expert Rev Neurother, 2021: p. 1-12. [Open article]


  • Jakimovski D, Szigeti K, Jaworski M 3rd, Ouf A, Weinstock-Guttman B, Zivadinov R, Benedict RHB, Differential Diagnosis of Cognitive Decline in Elderly Individuals With Multiple Sclerosis. Cogn Behav Neurol 2020;33:294-300. [Open article]
  • Jakimovski D, Bergsland N, Dwyer MG, Hagemeier J, Ramasamy DP, Szigeti K, Guttuso T, Lichter D, Hojnacki D, Weinstock-Guttman B, Benedict RHB, Zivadinov R, Long-standing multiple sclerosis neurodegeneration: volumetric magnetic resonance imaging comparison to Parkinson's disease, mild cognitive impairment, Alzheimer's disease, and elderly healthy controls. Neurobiol Aging, 2020. 90: p. 84-92. [Open article]
  • Vaughn CB, Jakimovski D, Kavak KS, Ramanathan M, Benedict RHB, Zivadinov R, Weinstock-Guttman B, Epidemiology and treatment of multiple sclerosis in elderly populations. Nat Rev Neurol, 2019. 15(6): p. 329-342. [Open article]


  • Vaughn CB, Jakimovski D, Kavak KS, Ramanathan M, Benedict RHB, Zivadinov R and Weinstock-Guttman B (2019). "Epidemiology and treatment of multiple sclerosis in elderly populations." Nat Rev Neurol 15(6): 329-342. [Open article]
  • Jakimovski D, Weinstock-Guttman B, Roy S, Jaworski M, 3rd, Hancock L, Nizinski A, Srinivasan P, Fuchs TA, Szigeti K, Zivadinov R and Benedict RHB (2019). "Cognitive Profiles of Aging in Multiple Sclerosis." Front Aging Neurosci 11: 105. [Open article]
  • Ghione E, Bergsland N, Dwyer MG, Hagemeier J, Jakimovski D, Paunkoski I, Ramasamy DP, Carl E, Hojnacki D, Kolb C, Weinstock-Guttman B and Zivadinov R (2019). "Aging and Brain Atrophy in Multiple Sclerosis." J Neuroimaging 29(4): 527-535. [Open article]
  • Bergsland N, Zivadinov R, Schweser F, Hagemeier J, Lichter D and Guttuso T, Jr. (2019). "Ventral posterior substantia nigra iron increases over 3 years in Parkinson's disease." Mov Disord 34(7): 1006-1013. [Open article]
  • Bergsland N, Tavazzi E, Schweser F, Jakimovski D, Hagemeier J, Dwyer MG and Zivadinov R (2019). "Targeting Iron Dyshomeostasis for Treatment of Neurodegenerative Disorders." CNS Drugs 33(11): 1073-1086. [Open article]


  • Roy S, Drake A, Snyder S, Cline B, Khan A, Fuchs T, Zivadinov R, Weinstock-Guttman B, Szigeti K and Benedict RHB (2018). "Preliminary investigation of cognitive function in aged multiple sclerosis patients: Challenges in detecting comorbid Alzheimer's disease." Mult Scler Relat Disord 22: 52-56. [Open article]
  • Guttuso T, Jr., Bergsland N, Hagemeier J, Lichter DG, Pasternak O and Zivadinov R (2018). "Substantia Nigra Free Water Increases Longitudinally in Parkinson Disease." AJNR Am J Neuroradiol 39(3): 479-484. [Open article]


  • Woodward MR, Dwyer MG, Bergsland N, Hagemeier J, Zivadinov R, Benedict RH and Szigeti K (2017). "Olfactory identification deficit predicts white matter tract impairment in Alzheimer's disease." Psychiatry Res Neuroimaging 266: 90-95. [Open article]


  • Zivadinov R, Jakimovski D, Gandhi S, Ahmed R, Dwyer MG, Horakova D, Weinstock-Guttman B, Benedict RR, Vaneckova M, Barnett M and Bergsland N (2016). "Clinical relevance of brain atrophy assessment in multiple sclerosis. Implications for its use in a clinical routine." Expert Rev Neurother: 1-17. [Open article]
  • Sanai SA, Saini V, Benedict RH, Zivadinov R, Teter BE, Ramanathan M and Weinstock-Guttman B (2016). "Aging and multiple sclerosis." Mult Scler 22(6): 717-725. [Open article]
  • Hagemeier J, Woodward MR, Rafique UA, Amrutkar CV, Bergsland N, Dwyer MG, Benedict R, Zivadinov R and Szigeti K (2016). "Odor identification deficit in mild cognitive impairment and Alzheimer's disease is associated with hippocampal and deep gray matter atrophy." Psychiatry Res 255: 87-93. [Open article]
  • Gupta S, Zivadinov R, Ramanathan M and Weinstock-Guttman B (2016). "Optical coherence tomography and neurodegeneration: are eyes the windows to the brain?" Expert Rev Neurother: 1-11. [Open article]


  • Mak E, Dwyer MG, Ramasamy DP, Au WL, Tan LC, Zivadinov R and Kandiah N (2015). "White Matter Hyperintensities and Mild Cognitive Impairment in Parkinson's Disease." J Neuroimaging 25(5): 754-760. [Open article]


  • Mak E, Bergsland N, Dwyer MG, Zivadinov R and Kandiah N (2014). "Subcortical atrophy is associated with cognitive impairment in mild Parkinson disease: a combined investigation of volumetric changes, cortical thickness, and vertex-based shape analysis." AJNR Am J Neuroradiol 35(12): 2257-2264. [Open article]


  • Alves G, Pedersen KF, Bloem BR, Blennow K, Zetterberg H, Borm GF, Dalaker TO, Beyer MK, Aarsland D, Andreasson U, Lange J, Tysnes OB, Zivadinov R and Larsen JP (2013). "Cerebrospinal fluid amyloid-beta and phenotypic heterogeneity in de novo Parkinson's disease." J Neurol Neurosurg Psychiatry 84(5): 537-543. [Open article]


  • Hagemeier J, Geurts JJ and Zivadinov R (2012). "Brain iron accumulation in aging and neurodegenerative disorders." Expert Rev Neurother 12(12): 1467-1480. [Open article]


  • Dalaker TO, Zivadinov R, Ramasamy DP, Beyer MK, Alves G, Bronnick KS, Tysnes OB, Aarsland D and Larsen JP (2011). "Ventricular enlargement and mild cognitive impairment in early Parkinson's disease." Mov Disord 26(2): 297-301. [Open article]


  • Dalaker TO, Zivadinov R, Larsen JP, Beyer MK, Cox JL, Alves G, Bronnick K, Tysnes OB, Antulov R, Dwyer MG and Aarsland D (2010). "Gray matter correlations of cognition in incident Parkinson's disease." Mov Disord 25(5): 629-633. [Open article]


  • Dalaker TO, Larsen JP, Dwyer MG, Aarsland D, Beyer MK, Alves G, Bronnick K, Tysnes OB and Zivadinov R (2009). "White matter hyperintensities do not impact cognitive function in patients with newly diagnosed Parkinson's disease." Neuroimage 47(4): 2083-2089. [Open article]
  • Dalaker TO, Larsen JP, Bergsland N, Beyer MK, Alves G, Dwyer MG, Tysnes OB, Benedict RH, Kelemen A, Bronnick K and Zivadinov R (2009). "Brain atrophy and white matter hyperintensities in early Parkinson's disease(a)." Mov Disord 24(15): 2233-2241. [Open article]


  • Zorzon M, Capus L, Pellegrino A, Cazzato G and Zivadinov R (2002). "Familial and environmental risk factors in Parkinson's disease: a case-control study in north-east Italy." Acta Neurol Scand 105(2): 77-82. [Open article]