As part of the University at Buffalo, we are dedicated to high quality academic research, with a focus on translational use of quantitative neuroimaging metrics in neurological diseases and disorders like MS, Alzheimer’s, and stroke. We have published over 500 scholarly articles in peer-reviewed journals.
We provide cutting-edge quantitative outcome analytics for clinical and preclinical researchers and sponsors. We combine standards-based approaches with research expertise to deliver accurate, precise measures in compliance with regulatory oversight.
A key part of our mission at BNAC is to teach. We disseminate knowledge and train future neuroimagers, trained masters, and PhD students. We host fellowships for visiting doctors and research scholars. BNAC faculty have mentored and co-mentored hundreds of PhD students, MSc students, MD students, undergraduate students, neuroimaging fellows, and neurology residents.
Precise, advanced neuroimaging metrics to measure treatment effects while maximizing statistical power.
Full coordination with participating imaging centers from study initiation, individual site on-boarding, image acquisition, and analysis.
Strict adherence to the highest standards and regulatory requirements, including FDA/EMA, GCP, and ISO 9001:2015.
Buffalo Neuroimaging Analysis Center (BNAC) director and University at Buffalo Professor of Neurology Robert Zivadinov, MD, PhD, is among six UB faculty honored as recipients of the 2022 State University of New York Chancellor’s Award for Excellence in Scholarship and Creative Activities. The SUNY system-wide Chancellor’s Awards recognize “consistently superior professional achievement and the ongoing pursuit of excellence” and the award for Excellence in Scholarship and Creative Activities specifically recognizes “those who engage actively in scholarly and creative pursuits beyond their teaching responsibilities.”
Initiating MS Research Breakthroughs While Building on Consensus
In a recent University at Buffalo’s Department of Neurology “Grand Rounds” presentation to research colleagues, doctoral candidates, and other students, BNAC Director Robert Zivadinov, MD, PhD, provided a comprehensive discussion of how a combination of traditional and novel imaging methods open the door wider to targeting microglia activation as a viable MS therapy. New imaging methods used in the study make it possible or easier to reliably assess microglia activation in living patients in addition to guiding pharmaceutical companies developing new microglia-focused MS treatments.
Zivadinov and his BNAC colleagues are delivering therapy-accelerating imaging of microglia activation, a long-trusted but hard-to-measure biomarker for secondary-progressive multiple sclerosis (SPMS). Currently it is not possible to predict who will eventually develop SPMS in which lost or damaged nerves worsen MS symptoms.
The first head-to-head comparison using microglia imaging of two FDA-approved disease-modifying treatments (DMTs) for multiple sclerosis is underway. Watch Center Director Robert Zivadinov, MD, PhD explain a study underway at the Buffalo Neuroimaging Analysis Center (BNAC) on NeurologyLive®.
The Annette Funicello Research Fund for Neurological Diseases (AFRFND) has awarded a $100,000 challenge grant to the Buffalo Neuroimaging Analysis Center (BNAC) in support of the center’s groundbreaking study of people with advanced-stage progressive Multiple Sclerosis. The grant is part of an ongoing campaign that, so far, has raised over $400,000 toward the overall goal of $1 million to underwrite this multi-year, investigator-initiated study.
Time Course of Lesion-induced Atrophy in Multiple Sclerosis.
-April 8, 2022
Cerebral Blood Flow Dependency on Systemic Arterial Circulation in Progressive Multiple Sclerosis.
-April 1, 2022
Functional Network Dynamics and Decreased Conscientiousness in Multiple Sclerosis.
-October 29, 2021
Thalamic Dorsomedial Nucleus Free Water Correlates with Cognitive Decline in Parkinson's Disease.
-June 3, 2021
Director of IT and Neuroinformatics Development
BNAC Director
Director of Sequence Development
