A cornerstone of the Buffalo Neuroimaging Analysis Center (BNAC) approach is the conviction that quantitative MRI measures can and should be used by physicians to aid in diagnosis/prognosis and in decisions regarding disease modifying therapy. In the field of Multiple Sclerosis in particular, the BNAC has identified four quantitative MRI variables that are reliable markers of disease progression, and is creating Quantitative MRI Reports on an individual basis. All four variables are graphed against normal control values. Furthermore, longitudinal analysis allows for the detection of very small changes in MRI variables that would be otherwise imperceptible even to a trained eye.

Through partnership with physicians and MRI centers, the BNAC is able to provide these reports in real time within hours of scan completion and included with MRI films, allowing to the physician to obtain both a quantitative and a qualitative impression of a patient’s condition simultaneously.

Recently, BNAC began to perform on a routine basis voxel-wise based dynamic lesion method of T2-LV classification into new, stable, resolving, and atrophied T2-LVs in patients with multiple sclerosis. BNAC is expanding this approach to patients with brain tumors.

Sample report: