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The Buffalo Neuroimaging Analysis Center (BNAC) continually pursues development of new scanning sequences, both conventional and non-conventional. Several active projects are under way on cortical imaging, including development of sequences for better detection of cortical lesions in a variety of neurological disorders. Applying new imaging strategies is also part of BNAC’s aims. Specific areas of interest include advanced quantitative tissue parameter mapping, MR spectroscopy, molecular imaging using ultra small particle ion oxide (USPIO), and a combination of PET and MRI imaging. BNAC’s imaging program spans the whole translational range from preclinical to clinical MRI.

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fMRI is not fully used clinically for diagnosis or monitoring of different diseases. Rather it has been used in research settings to examine the neural correlates of known motor and neuropsychological deficits in patients with a variety of neurological disorders. BNAC conducts fMRI research in patients with multiple sclerosis, stroke, mild cognitive impairment, auditory, and behavioral problems, using paradigms to assess motor ability, processing speed, working memory, and visual tasks.