Since its inception, the Buffalo Neuroimaging Analysis Center (BNAC) has been establishing itself as a world leader in the application of different magnetic resonance imaging (MRI) techniques to the study of multiple sclerosis (MS) and other neurodegenerative diseases. Numerous peer review articles reflect this high quality research activity, and to date, the BNAC has contributed more than 150 articles to the field of neuroimaging and neuroscience. Furthermore, the BNAC research projects have involved international collaboration with a variety of clinicians and scientists pursuing the use of quantitative MRI to study brain disorders.